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Joshua Bomser
Campbell Hall 343B
(614) 247 6622
jbomser@ehe.osu.edu
Associate Professor
Molecular Nutrition and Functional Foods
View Joshua Bomser's curriculum vitae.
B.S. University of Maryland - College Park. Foods and Nutrition
Ph.D.University of Illinois- Urbana/Champaign. Nutritional Sciences
Post-doc. University of California, Berkeley. Pesticide Toxicology
2004-Present Assistant Professor, Department of Human Nutrition, The Ohio State University.
2000-2004 Assistant Professor, Department of Food Science and Technology, The Ohio State University. Functional Foods in Disease Prevention
1998-2000 Post-Doctoral Fellow, Department of Environmental Chemistry and Toxicology, University of California-Berkeley. Studied the toxic effects of pesticides on mammalian signal transduction pathways. Primary Investigator: Dr. John Casida
1993-1998 Graduate Research Assistant, Division of Nutritional Sciences, University of Illinois at Urbana-Champaign. Conducted Ph.D. thesis research examining the anti-cancer activity of natural products. Thesis advisor : Dr. Keith W. Singletary
1992-1993 Research Assistant, United States Department of Agriculture (USDA), Weed Science Lab Beltsville, Maryland. Bioassayed plant products for herbicidal activity. Advisor: Dr. John Lydon
Prevention of chronic disease by non-nutritive dietary components. Specific interest in the role of carotenoids in the prevention of cataract and age-related macular degeneration.
Our laboratory is interested in identifying the cellular and molecular mechanisms by which dietary constituents influence chronic disease progression. Specifically, we are focused on elucidating the mechanisms by which carotenoids (lutein and zeaxanthin) and soy isoflavones inhibit cataract development and prostate cancer, respectively. Additional projects in the laboratory involve non-thermal processing effects on functional dietary ingredients and the role of red wine components in preventing cardiovascular disease
Chureeporn Chitchumroonchokchai , Joshua A. Bomser Jayme E. Glamm and Mark L. Failla (in press) Xanthophylls and a-tocopherol decrease UVB-induced lipid peroxidation and stress signaling in human lens epithelial cells. Journal of Nutrition.
Colitz, CMH., Long, AC. And Bomser, JA (in press) Apoptotic and necrotic mechanisms of stress-induced human lens epithelial cell death. Experimental Biology and Medicine.
Erik R. Olson, Jennifer E. Naugle, Xiaojin Zhang, J. Gary Meszaros, and Joshua Bomser (in press) Resveratrol inhibits proliferation of cardiac fibroblasts via inhibition of the ERK 1/2 signaling cascade. American Journal of Physiology-Heart and Lung.
Lado, B., Bomser, J., Dunne, P., and Yousef, A. (2004) Pulsed Electric Field Alters Molecular Chaperone Expression and Sensitizes Listeria monocytogenes to Heat. Applied and Environmental Microbiology, 70(5):2289-2295.
Kent K, Bomser J. (2003) Bovine pituitary extract provides remarkable protection against oxidative stress in human prostate epithelial cells. In Vitro Cell Dev Biol Anim. 39(8):388-394.
Zhang YC, Albrecht D, Bomser J, Schwartz SJ, Vodovotz Y. (2003) Isoflavone profile and biological activity of soy bread. J Agric Food Chem. 17; 51(26): 7611-6.
Boileau, T., Bray, TM. and Bomser JA. (2003) UVA radiation modulates nuclear factor kappa B (NFkB) activity in human lens epithelial cells. J. Biochem Mol. Toxicol. 17(2): 108-113.
Kent, K., Harper, WJ. and Bomser, JA. (2003) Effect of whey protein isolate on glutathione concentrations and oxidative damage in human prostate epithelial cells. Toxicology In Vitro 17, 27-33.
Bomser, J.A. (2002) Ultraviolet radiation selectively induces mitogen-activated protein kinase cascades in Human lens epithelial cells. J. Biochem Mol. Toxicol. 16(1), 33-39.
Bomser, J.A., Quistad, G.B. and Casida, J.E. (2002) Chlorpyrifos oxon potentiates diacylglycerol-induced extracellular signal-regulated kinase (ERK 44/42) activation via diacylglycerol lipase inhibition. Toxicology and Applied Pharmacology 178, 29-36.
University Seed Grant (PI) Effects of Lutein and Zeaxanthin on Ultraviolet and
Near-Ultraviolet Light-Induced Oxidative Stress in Retinal Pigment Epithelial Cells $18,000
2000-2002
OARDC Interdisciplinary Grant (PI) Carotenoids and Age-Related Cataracts $100,000 2001-current
USDA Initiative for Future Agriculture and Food Systems Program (Co-PI) Model System for Functional Foods: Tomato Products Containing Soy $1,275,000, 2002-Current
CAAPS, National Science Foundation (co-PI) Mechanisms of Microbial Inactivation
by PEF $44,896 2002-2004
Ohio State University Honors and Scholars Program (PI) Food: Fact and Fiction?
$4,000, 2003-current
FST 201 : The Science of Food
HN 761 : Advance Lipid Metabolism